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Conference programme

Childhood Cancer 2012 brought together an outstanding line-up of speakers from a range of different research disciplines to speak on aspects of childhood cancer and early exposures.

The panel of invited speakers were joined by the authors of 25 submitted abstracts, representing a cross-section of over 100 excellent abstracts submitted for poster presentation.

We are pleased to be able to make available videos of some of the presentations and copies of some of the speakers' slides. You can access these by clicking on the links next to speakers' names below.

Tuesday, 24th April 2012

08:00 Open for registration
09:45

SESSION 1 - Setting the scene
Chair:

  Welcome on behalf of CHILDREN with CANCER UK
Professor Denis Henshaw | View welcome video
  Opening address
Professor Sir Alan Craft | View slides | View opening address
  Keynote address
Professor David Barker | View slides | View presentation
The intrauterine origins of cancer
  Mr Charles Stiller | View slides | View presentation
National and international childhood cancer incidence and time trends
11:20 Coffee
11:45

SESSION 2 - The prognosis for children diagnosed with cancer in the 21st century
Chair:

  Dr Anupama Rao
Acute lymphoblastic leukaemia
  Dr Darren Hargrave
Childhood CNS tumours
  Professor Kathy Pritchard-Jones
Childhood non-CNS solid tumours
  Discussion | View discussion
13:15 Lunch and posters
14:30

SESSION 3 - Genetic and epigenetic aspects of childhood cancer risk
Chair:

  Professor Nazneen Rahman | View slides | View presentation
Genetic susceptibility to childhood cancer
  Professor Joseph Wiemels | View slides | Presentation pending publication of data
Epigenetic changes and childhood cancer
  Proffered paper | View slides | View presentation
Dr Elizabeth Perdeaux - GWAS identifies six loci, implicating the planar cell polarity pathway and the MYCN-DDX1 2p24.3 amplicon region in Wilms tumor susceptibility
  Proffered paper
Dr Amy Sherborne - Developmental timing of mutations in childhood leukaemia: insights from genome sequencing in twin pairs with ALL
  Proffered paper | View slides | View presentation
Sanne van Otterdijk - Does childhood leukaemia develop in cells which are pre-primed by the presence of aberrant patterns of DNA methylation?
  Proffered paper | View slides | View presentation
Dr Ariadna Mendoza-Naranjo - ErbB4 is a novel driver of metastasis and chemoresistance in Ewing sarcoma
  Discussion | View discussion
16:30 Tea and posters
17:00

SESSION 4 - Birth characteristics
Chair:

  Proffered paper | View slides | View presentation
Dr Lisbeth Samsø Schmidt - Birth characteristics and the subsequent risk of childhood CNS tumours and Incidence of childhood CNS tumours in the Nordic countries
  Proffered paper | View presentation
Dr Kate O'Neill - Infant birth weight as a risk factor for childhood cancer
  Proffered paper
Professor Peggy Reynolds - Birth defects as clues to the aetiology of cancer in children
  Proffered paper | View slides | View presentation
Dr Jérémie Rudant - Use of fertility treatments and childhood acute leukaemia: the ESCALE study
  Discussion | View discussion
18:00 Wine reception and poster viewing

Wednesday, 25th April 2012

08:30

SESSION 5 - Air pollution and smoking
Chair:

  Introduction to air pollution and smoking
Professor Denis Henshaw | View introduction
  Dr Mathuros Ruchirawat
DNA damage and repair in children exposed to benzene and carcinogenic compounds in ambient air
  Proffered paper
Professor Peggy Reynolds - Hazardous air pollutants and risk of childhood brain tumours in California
  Proffered paper
Dr Julia Heck - Traffic-related air pollution and childhood cancers in Los Angeles county
  Proffered paper | View slides | Presentation not yet available
Dr Catherine Metayer - Effects of tobacco smoking on the risks of childhood acute lymphocytic and myeloid leukaemias, by phenotypic and cytogenetic subtype
  Proffered paper
Professor Elizabeth Milne - Parental pre-natal smoking and risk of childhood acute lymphoblastic leukaemia
  Proffered paper | View slides | View presentation
Jessica Trimis - Parental smoking and risk of childhood brain tumours by functional polymorphisms in polycyclic aromatic hydrocarbon metabolism genes
  Discussion | View discussion
10:30 Coffee and posters
11:00

SESSION 6 - Aspartame, pesticides and other chemical exposures
Chair:

  Dr Morando Soffritti | View slides | View presentation
Aspartame and sucralose: the experimental evidence of cancer risk
  Professor Claire Infante-Rivard | View slides | View presentation
Exposure to pesticides and childhood cancer risk
  Proffered paper | View slides | View presentation
Dr Gisele Moledo de Vasconcelos - PON1 polymorphisms and the risk of Wilms tumour
  Proffered paper
Dr Sergio Koifman - Pregnancy, maternal exposure to hair dyes or hair straightening cosmetics and early age leukaemia in Brazil
  Proffered paper | View slides | View presentation
Dr Lucia Miligi - SETIL study: risk of childhood cancers in relation to parental occupational exposure
  Discussion View discussion
12:45 Lunch and poster viewing
13:45

SESSION 7 - Non-ionising radiation
Chair:

  Professor Richard Stevens | View slides | View presentation
Electric light, circadian disruption and cancer risk
  Professor Elisabeth Cardis | View slides | View presentation
Rationale for the IARC 2b classification for ELF and RF EMF
  Professor Denis Henshaw | View slides | View presentation
How might power frequency magnetic fields cause increased risk of childhood leukaemia?
  Discussion | View discussion
15:30 Tea and posters
16:00

SESSION 8 - Brain tumours, mobile phones and childhood cancer
Chair:

  Professor Geoff Pilkington | View slides | View presentation
Brain tumours: complexity in type, biology and origin
  Professor Dariusz Leszczynski | View slides | View presentation
Possible mechanism of cell phone radiation-induced brain cancer
  Proffered paper
Tina Veje Andersen - Mobile phone use, patterns of infectious disease, social contacts in early life and brain tumours in children and adults: an international case-control study (CEFALO)
  Discussion | View discussion
17:30 Day two close
19:30 CONFERENCE DINNER, Royal College of Physicians

Thursday, 26th April 2012

08:30

SESSION 9 - Ionising radiation
Chair:

  Professor Richard Wakeford | View slides | View presentation
Ionising radiation and childhood cancer overview
  Professor Yuri Dubrova | View slides | View presentation
Radiation genetics, epigenetics and effects on clock genes
  Professor Kevin Prise
Bystander signalling - a future perspective
  Proffered paper | View slides | View presentation
Dr Richard McNally - Increasing incidence and geographical analysis of thyroid cancer in Great Britain, 1976 to 2005
  Discussion | View discussion
10:15 Coffee and posters
10:45

SESSION 10 - Infection and immunity
Chair:

  Dr Kevin Urayama | View slides | Presentation not available
Early life exposures to infectious agents and childhood cancer risk
  Proffered paper | Slides and presentation not yet available
Srividya Swaminathan - Infectious origins of childhood leukaemia
  Proffered paper | View slides | View presentation
Dr Giorgia Randi - A childhood leukaemia cluster in Milan: possible role of pandemic AH1N1 swine flu virus
  Discussion | View discussion
12:00 Lunch and posters
13:00

SESSION 11 - Diet
Chair:

  Professor Eleni Petridou | View slides | View presentation
Maternal and child dietary habits and childhood leukaemia risk
  Proffered paper | View slides | View presentation
Professor Anand Chokkalingam - Folate and childhood leukaemia risk
  Proffered paper | View slides | View presentation
Alicia Amigou - Folic acid supplementation, MTHFR and MTRR polymorphisms and the risk of childhood leukaemia: the ESCALE study
  Discussion | View discussion
14:00 Tea Break
14:30

SESSION 12 - What positive steps can be taken to reduce the risk of childhood cancer?
Chair: Professor Richard Stevens

  Professor Annie Sasco | View slides | View presentation
Alliance of prevention and precaution for childhood cancer control
  Proffered paper | View slides | View presentation
Professor Pat Buffler - The Childhood Leukemia International Consortium (CLIC)
  Proffered paper | View slides | View presentation
Professor Terry Dwyer - The International Childhood Cancer Cohort Consortium (I4C)
  Dr Somdat Mahabir
Report on NIH efforts to tackle early-life exposures and cancer
  Panel discussion: "In terms of public health policy what positive steps can be taken to reduce the risk of childhood cancer?" - leading into a general discussion: "What are the key messages from the conference?"
View discussions: Panel discussion | General discussion
16:30

CLOSING SESSION

  Poster prize presentation | View prize presentations
Closing talk | View closing session and talk
17:00 Close of conference

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(formerly CHILDREN with LEUKAEMIA)
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London WC1N 3JQ
Tel: 020 7404 0808
Fax: 020 7404 3666

Registered Charity Number: 298405
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