Childhood Cancer 2012 is bringing together an outstanding line-up of speakers from a range of different research disciplines to speak on aspects of childhood cancer and early exposures.
Joining the panel of invited speakers are the authors of 25 submitted abstracts, representing a cross-section of over 100 excellent abstracts submitted for poster presentation.
A list of accepted abstracts will be available shortly.
Tuesday, 24th April 2012 |
| 08:00 |
Open for registration |
| 09:45 |
SESSION 1 - Setting the scene
Chair:
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Welcome on behalf of CHILDREN with CANCER UK
Professor Denis Henshaw | View welcome video
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Opening address
Professor Sir Alan Craft | View slides | View opening address
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Keynote address
Professor David Barker
The intrauterine origins of cancer |
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Mr Charles Stiller | View slides | View presentation
National and international childhood cancer incidence and time trends
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| 11:20 |
Coffee |
| 11:45 |
SESSION 2 - The prognosis for children diagnosed with cancer in the 21st century
Chair:
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Dr Anupama Rao
Acute lymphoblastic leukaemia |
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Dr Darren Hargrave
Childhood CNS tumours |
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Professor Kathy Pritchard-Jones
Childhood non-CNS solid tumours |
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Discussion | View discussion
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| 13:15 |
Lunch and posters |
| 14:30 |
SESSION 3 - Genetic and epigenetic aspects of childhood cancer risk
Chair:
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Professor Nazneen Rahman | View slides | View presentation
Genetic susceptibility to childhood cancer
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Professor Joseph Wiemels
Epigenetic changes and childhood cancer |
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Proffered paper | View slides | View presentation
Dr Elizabeth Perdeaux - GWAS identifies six loci, implicating the planar cell polarity pathway and the MYCN-DDX1 2p24.3 amplicon region in Wilms tumor susceptibility
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Proffered paper
Dr Amy Sherborne - Developmental timing of mutations in childhood leukaemia: insights from genome sequencing in twin pairs with ALL |
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Proffered paper | View slides | View presentation
Sanne van Otterdijk - Does childhood leukaemia develop in cells which are pre-primed by the presence of aberrant patterns of DNA methylation?
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Proffered paper | View slides | View presentation
Dr Ariadna Mendoza-Naranjo - ErbB4 is a novel driver of metastasis and chemoresistance in Ewing sarcoma
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Discussion | View discussion
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| 16:30 |
Tea and posters |
| 17:00 |
SESSION 4 - Birth characteristics
Chair:
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Proffered paper
Dr Lisbeth Samsø Schmidt - Birth characteristics and the subsequent risk of childhood CNS tumours and Incidence of childhood CNS tumours in the Nordic countries |
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Proffered paper | Slides and presentation not available
Dr Kate O'Neill - Infant birth weight as a risk factor for childhood cancer |
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Proffered paper
Professor Peggy Reynolds - Birth defects as clues to the aetiology of cancer in children |
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Proffered paper | View slides | View presentation
Dr Jérémie Rudant - Use of fertility treatments and childhood acute leukaemia: the ESCALE study
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Discussion | View discussion
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| 18:00 |
Wine reception and poster viewing |
Wednesday, 25th April 2012 |
| 08:30 |
SESSION 5 - Air pollution and smoking
Chair:
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Introduction to air pollution and smoking
Professor Denis Henshaw | View introduction
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Dr Mathuros Ruchirawat
DNA damage and repair in children exposed to benzene and carcinogenic compounds in ambient air |
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Proffered paper
Professor Peggy Reynolds - Hazardous air pollutants and risk of childhood brain tumours in California |
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Proffered paper
Dr Julia Heck - Traffic-related air pollution and childhood cancers in Los Angeles county |
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Discussion |
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Proffered paper | View slides | Presentation not available
Dr Catherine Metayer - Effects of tobacco smoking on the risks of childhood acute lymphocytic and myeloid leukaemias, by phenotypic and cytogenetic subtype |
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Proffered paper
Professor Elizabeth Milne - Parental pre-natal smoking and risk of childhood acute lymphoblastic leukaemia |
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Proffered paper | View slides | View presentation
Jessica Trimis - Parental smoking and risk of childhood brain tumours by functional polymorphisms in polycyclic aromatic hydrocarbon metabolism genes
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Discussion | View discussion
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| 10:30 |
Coffee and posters |
| 11:00 |
SESSION 6 - Aspartame, pesticides and other chemical exposures
Chair:
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Dr Morando Soffritti | View slides | Presentation not available
Aspartame and sucralose: the experimental evidence of cancer risk |
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Professor Claire Infante-Rivard | View slides | View presentation
Exposure to pesticides and childhood cancer risk
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Proffered paper | View slides | View presentation
Dr Gisele Moledo de Vasconcelos - PON1 polymorphisms and the risk of Wilms tumour
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Proffered paper
Dr Sergio Koifman - Pregnancy, maternal exposure to hair dyes or hair straightening cosmetics and early age leukaemia in Brazil |
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Proffered paper | View slides | View presentation
Dr Lucia Miligi - SETIL study: risk of childhood cancers in relation to parental occupational exposure
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Discussion View discussion
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| 12:45 |
Lunch and poster viewing |
| 13:45 |
SESSION 7 - Non-ionising radiation
Chair:
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Professor Richard Stevens | View slides | View presentation
Electric light, circadian disruption and cancer risk
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Professor Elisabeth Cardis | View slides | View presentation
Rationale for the IARC 2b classification for ELF and RF EMF
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Professor Denis Henshaw | View slides | View presentation
How might power frequency magnetic fields cause increased risk of childhood leukaemia?
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Discussion | View discussion
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| 15:30 |
Tea and posters |
| 16:00 |
SESSION 8 - Brain tumours, mobile phones and childhood cancer
Chair:
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Professor Geoff Pilkington | View slides | View presentation
Brain tumours: complexity in type, biology and origin
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Professor Dariusz Leszczynski | View slides | View presentation
Possible mechanism of cell phone radiation-induced brain cancer
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Proffered paper
Tina Veje Andersen - Mobile phone use, patterns of infectious disease, social contacts in early life and brain tumours in children and adults: an international case-control study (CEFALO) |
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Discussion | View discussion
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| 17:30 |
Day two close |
| 19:30 |
CONFERENCE DINNER, Royal College of Physicians |
Thursday, 26th April 2012 |
| 08:30 |
SESSION 9 - Ionising radiation
Chair:
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Professor Richard Wakeford | View slides | View presentation
Ionising radiation and childhood cancer overview
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Professor Yuri Dubrova | View slides | View presentation
Radiation genetics, epigenetics and effects on clock genes
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Professor Kevin Prise
Bystander signalling - a future perspective |
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Proffered paper | View slides | View presentation
Dr Richard McNally - Increasing incidence and geographical analysis of thyroid cancer in Great Britain, 1976 to 2005
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Discussion | View discussion
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| 10:15 |
Coffee and posters |
| 10:45 |
SESSION 10 - Infection and immunity
Chair:
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Dr Kevin Urayama | View slides | Presentation not available
Early life exposures to infectious agents and childhood cancer risk |
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Proffered paper | Slides and presentation not available
Srividya Swaminathan - Infectious origins of childhood leukaemia |
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Proffered paper | View slides | View presentation
Dr Giorgia Randi - A childhood leukaemia cluster in Milan: possible role of pandemic AH1N1 swine flu virus
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Discussion | View discussion
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| 12:00 |
Lunch and posters |
| 13:00 |
SESSION 11 - Diet
Chair:
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Professor Eleni Petridou | View slides | View presentation
Maternal and child dietary habits and childhood leukaemia risk
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Proffered paper | View slides | View presentation
Professor Anand Chokkalingam - Folate and childhood leukaemia risk
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Proffered paper | View slides | View presentation
Alicia Amigou - Folic acid supplementation, MTHFR and MTRR polymorphisms and the risk of childhood leukaemia: the ESCALE study
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Discussion | View discussion
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| 14:00 |
Tea Break |
| 14:30 |
SESSION 12 - What positive steps can be taken to reduce the risk of childhood cancer?
Chair: Professor Richard Stevens
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Professor Annie Sasco | View slides | View presentation
Alliance of prevention and precaution for childhood cancer control
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Proffered paper | View slides | View presentation
Professor Pat Buffler - The Childhood Leukemia International Consortium (CLIC)
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Proffered paper | View slides | View presentation
Professor Terry Dwyer - The International Childhood Cancer Cohort Consortium (I4C)
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Dr Somdat Mahabir
Report on NIH efforts to tackle early-life exposures and cancer |
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Panel discussion: "In terms of public health policy what positive steps can be taken to reduce the risk of childhood cancer?" - leading into a general discussion: "What are the key messages from the conference?"
View discussions: Panel discussion | General discussion
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| 16:30 |
CLOSING SESSION
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Poster prize presentation | View prize presentations
Closing talk | View closing session and talk
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| 17:00 |
Close of conference |
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